Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein (MHC-HM434T)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and IMPKAGLLI peptide

Catalog: MHC-HM434T


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Product Description Recombinant Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and IMPKAGLLI peptide.

Product Background

Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.

Product Category

Recombinant Protein


HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer
MHC Form Tetramer
Allele HLA-A*24:02



Amino Acid Range

Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and IMPKAGLLI peptide
Molecular Weight The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer is greater than 95% as determined by SEC-HPLC.
Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer on Tris-Bis PAGE under Non reducing (N) condition. The purity is greater than 95%.

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