Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein (MHC-HM434T)
Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein (MHC-HM434T)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and IMPKAGLLI peptide
Catalog #MHC-HM434T
Regular price $750.00
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Product Description

Recombinant Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and IMPKAGLLI peptide.

Product Background

Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.

Product Category

Recombinant Protein / Antibody discovery / MHC

Protein

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer

Synonyms

Melanoma-associated antigen 3; MZ2-D; MZ2D; MZ2-D; CT1.3; MAGE-3; HLA-A*24:02; HLA-A2402

MHC Form

Tetramer

Allele

HLA-A*24:02

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and IMPKAGLLI peptide

Molecular Weight

The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%. Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%.
The purity of Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer is greater than 95% as determined by SEC-HPLC. The purity of Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer is greater than 95% as determined by SEC-HPLC.

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