Human MARCO Protein (MRO-HM102)
Human MARCO Protein (MRO-HM102)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser405-Val520
Catalog #MRO-HM102
Regular price $346.50
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Product Description

Recombinant Human MARCO Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ser405-Val520.

Product Background

Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP.

Product Category

Recombinant Protein / Antibody discovery

Protein

MARCO

Synonyms

MARCO; SCARA2; AI323439; Ly112

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ser405-Val520

Molecular Weight

The protein has a predicted MW of 13.8 kDa. Due to glycosylation, the protein migrates to 14-20 kDa based on Bis-Tris PAGE result.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS, 200mM L-arginine (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human MARCO on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human MARCO on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human MARCO is greater than 95% as determined by SEC-HPLC. The purity of Human MARCO is greater than 95% as determined by SEC-HPLC.

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