Human MARCO Protein (MRO-HM102)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser405-Val520

Catalog: MRO-HM102


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Product Description Recombinant Human MARCO Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ser405-Val520.

Product Background

Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP.

Product Category

Recombinant Protein


Synonyms MARCO; SCARA2; AI323439; Ly112



Amino Acid Range

Molecular Weight The protein has a predicted MW of 13.8 kDa. Due to glycosylation, the protein migrates to 14-20 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS, 200mM L-arginine (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human MARCO is greater than 95% as determined by SEC-HPLC.
Human MARCO on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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