Human Mature TGF beta 2 Protein (TG2-HM00M)
Human Mature TGF beta 2 Protein (TG2-HM00M)
Human Mature TGF beta 2 Protein (TG2-HM00M)
Human Mature TGF beta 2 Protein (TG2-HM00M)
Human Mature TGF beta 2 Protein (TG2-HM00M)
  • Express System: HEK293
  • Product Tag: No Tag
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala303-Ser414
Catalog #TG2-HM00M
Regular price $405.00
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Product Description

Recombinant Human Mature TGF beta 2 Protein is expressed from HEK293 without tag. It contains Ala303-Ser414.

Product Background

Transforming growth factor beta(2) (TGF-beta(2)), a growth regulator of human lens epithelial cells (HLECs), also regulates the death of these cells. TGF-beta(2)-induced apoptosis in HLECs was preceded by an induction of reactive oxygen species (ROS) and a decrease in glutathione in the intracellular content, indicating that this factor induces oxidative stress in HLECs.

Product Category

Recombinant Protein / Antibody discovery

Protein

Mature TGF beta 2

Synonyms

TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ala303-Ser414

Molecular Weight

The protein has a predicted MW of 12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

No Tag

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in 4mM HCl. Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 4mM HCl.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test). Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test).
Human Mature TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Mature TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.1 - 1 ng/ml (QC Test). Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.1 - 1 ng/ml (QC Test).

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