Name: Human Mature TGF beta 2 Protein (TG2-HM00M)
Brand: KactusBio
SKU: TG2-HM00M-100UG
Price: 445.5 USD
Availability: InStock

ELISA binding curve showing the interaction between human mature TGF beta 2 (no tag) and biotinylated human TGF-beta RII, mFc tag, with mean absorbance (OD450) plotted against the log concentration of the ligand.

Human Mature TGF beta 2 Protein (TG2-HM00M)

Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test).

Human Mature TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.1 - 1 ng/ml (QC Test).

Express System: HEK293
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test).
Amino Acid Range: Ala303-Ser414

Catalog #TG2-HM00M

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human Mature TGF beta 2 Protein (TG2-HM00M) Summary

Product Description	Recombinant Human Mature TGF beta 2 Protein is expressed from HEK293 without tag. It contains Ala303-Ser414.
Product Background	Transforming growth factor beta(2) (TGF-beta(2)), a growth regulator of human lens epithelial cells (HLECs), also regulates the death of these cells. TGF-beta(2)-induced apoptosis in HLECs was preceded by an induction of reactive oxygen species (ROS) and a decrease in glutathione in the intracellular content, indicating that this factor induces oxidative stress in HLECs.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Mature TGF beta 2 Protein (TG2-HM00M) Specifications/Details

Protein	Mature TGF beta 2
Synonyms	TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2
Accession	P61812-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala303-Ser414
Molecular Weight	The protein has a predicted MW of 12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test).
Product Tag	No Tag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 4mM HCl. Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in 4mM HCL. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human Mature TGF beta 2, No Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.53ug/ml determined by ELISA (QC Test).
	Human Mature TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.1 - 1 ng/ml (QC Test).