Name: Human MERTK/Mer Protein (MEK-HM101)
Brand: KactusBio
SKU: MEK-HM101-100UG
Price: 270.0 USD
Availability: InStock

Catalog #MEK-HM101

Size

100UG

500UG

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Product Description	Recombinant Human MERTK/Mer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Ile505.
Product Background	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.
Product Category	Recombinant Protein / Antibody discovery

Protein	MERTK/Mer
Synonyms	MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12
Accession	Q12866-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala21-Ile505
Molecular Weight	The protein has a predicted MW of 53.73 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human MERTK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human MERTK is greater than 95% as determined by SEC-HPLC.