Name: Human MERTK/Mer Protein (MEK-HM301)
Brand: KactusBio
SKU: MEK-HM301-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human MERTK, mFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Human GAS6, His Tag with the EC50 of 3.55ug/ml determined by ELISA (QC Test).
Amino Acid Range: Ala21-Ile505

Catalog #MEK-HM301

Size

100UG

500UG

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Human MERTK/Mer Protein (MEK-HM301) Summary

Product Description	Recombinant Human MERTK/Mer Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ala21-Ile505.
Product Background	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human MERTK/Mer Protein (MEK-HM301) Specifications/Details

Protein	MERTK/Mer
Synonyms	MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12
Accession	Q12866-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala21-Ile505
Molecular Weight	The protein has a predicted MW of 78.9 kDa. Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human MERTK, mFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Human GAS6, His Tag with the EC50 of 3.55ug/ml determined by ELISA (QC Test).
Product Tag	C-mFc
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human MERTK, mFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Human GAS6, His Tag with the EC50 of 3.55ug/ml determined by ELISA (QC Test).
	Human MERTK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human MERTK is greater than 95% as determined by SEC-HPLC.

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