Product Description |
Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile22-Leu173. |
Product Background |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. |
Product Category |
Recombinant Protein |
Target |
MFAP5 |
Synonyms |
MFAP-5; MAGP-2; MAGP2; MP25; AAT9 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ile22-Leu173 |
Molecular Weight |
The protein has a predicted MW of 44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human MFAP5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human MFAP5 is greater than 95% as determined by SEC-HPLC. |
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