- Express System: HEK293
- Product Tag: C-His
- Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
- Activity: Immobilized Human MICA*007:01:05, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.15ug/ml determined by ELISA (QC Test). See testing image for detail.
- Amino Acid Range: Glu24-Thr309
Product Description |
Recombinant Human MICA*007:01:05 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu24-Thr309. |
Product Background |
MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.. |
Product Category |
Recombinant Protein |
Target |
MICA*007:01:05 |
Synonyms |
C5NT78; MICA; MICA*007:01:05 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu24-Thr309 |
Molecular Weight |
The protein has a predicted MW of 34.51 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human MICA*007:01:05, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.15ug/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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