Product Description |
Recombinant Human MICB*005:02:15 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Asp309. |
Product Background |
MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. |
Product Category |
Recombinant Protein |
Target |
MICB*005:02:15 |
Synonyms |
MICB; MIC-B; PERB11.2;MICB*005:02:15 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala23-Asp309 |
Molecular Weight |
The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human MICB*005:02:15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.28ug/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human MICB*005:02:15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.28ug/ml determined by ELISA (QC Test). |
|
|
Human MICB*005:02:15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human MICB*005:02:15 is greater than 95% as determined by SEC-HPLC. |
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