Human MICB*008:01:08 Protein (MIC-HM110)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Human MICB*008:01:08, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala23-Asp309
Catalog #MIC-HM110
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Product Description
 Recombinant Human MICB*008:01:08 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Asp309.
Product Background
 MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Product Category
 Recombinant Protein
Target
 MICB*008:01:08
Synonyms
 MICB; MIC-B; PERB11.2;MICB*008:01:08
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala23-Asp309
Molecular Weight
 The protein has a predicted MW of 34.32 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human MICB*008:01:08, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human MICB*008:01:08, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test).
Human MICB*008:01:08 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human MICB*008:01:08 is greater than 95% as determined by SEC-HPLC.

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