Name: Human MICB*014:01:08 Protein (MIC-HM108)
Brand: KactusBio
SKU: MIC-HM108-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Human MICB*014:01:08, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.63ug/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ala23-Asp309

Catalog #MIC-HM108

Size

100UG

500UG

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Product Description	Recombinant Human MICB*014:01:08 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Asp309.
Product Background	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Product Category	Recombinant Protein / Antibody discovery

Protein	MICB*014:01:08
Synonyms	MICB; MIC-B; PERB11.2;MICB*014:01:08
Accession	A0A7D9D6Y8
Species	Human
Biotinylated	no
Amino Acid Range	Ala23-Asp309
Molecular Weight	The protein has a predicted MW of 34.33 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human MICB*014:01:08, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.63ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human MICB*014:01:08, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.63ug/ml determined by ELISA (QC Test).
	Human MICB*014:01:08 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human MICB*014:01:08 is greater than 95% as determined by SEC-HPLC.