Human Midkine Protein (MID-HE401)
Catalog: MID-HE401
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| Product Description | Recombinant Human Midkine Protein is expressed from E.coli with His tag and Avi Tag at the N-Terminus.It contains Val21-Asp143. |
Product Background |
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. |
Product Category |
Recombinant Protein |
Target |
Midkine |
| Synonyms | MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MEK; MK1; MKARAP; NEGF2 |
Gene/Protein ID |
P21741-1 |
Species |
Human |
Exact Sequence |
Val21-Asp143 |
| Molecular Weight | The protein has a predicted MW of 16.46 kDa same as Tris-Bis PAGE result. |
Product Tag |
N-His-Avi |
Express System |
E.coli |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Human Midkine on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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