Product Description |
Recombinant Human MOG/Myelin Oligodendrocyte Glycoprotein Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly30-Gly154. |
Product Background |
Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). |
Product Category |
Recombinant Protein |
Target |
MOG/Myelin Oligodendrocyte Glycoprotein |
Synonyms |
MOG; MGC26137; MOG Ig-AluB; MOGIG2; BTN6; BTNL11; NRCLP7 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly30-Gly154 |
Molecular Weight |
The protein has a predicted MW of 15.4 kDa. Due to glycosylation, the protein migrates to 20-23 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human MOG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human MOG is greater than 95% as determined by SEC-HPLC. |
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