• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser27-Thr150
Catalog #BMP-HM2R2
Price
Regular price $34650
Regular price Sale price $34650
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Human/Mouse BMPR2 Protein (BMP-HM2R2) Summary

Product Description

 Recombinant Human/Mouse BMPR2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser27-Thr150.

Product Background

 Bone morphogenetic protein type 2 receptor (BMPR2) is one of the transforming growth factor-β (TGF-β) superfamily receptors, performing diverse roles during embryonic development, vasculogenesis, and osteogenesis. Human BMPR2 consists of 1,038 amino acids, and contains functionally conserved extracellular, transmembrane, kinase, and C-terminal cytoplasmic domains. Bone morphogenetic proteins (BMPs) engage the tetrameric complex, composed of BMPR2 and its corresponding type 1 receptors, which initiates SMAD proteins-mediated signal transduction leading to the expression of target genes implicated in the development or differentiation of the embryo, organs and bones.

Human/Mouse BMPR2 Protein (BMP-HM2R2) Specifications/Details

Protein
 BMPR2
Synonyms
 BMPR-2; BMPR-II; PPH1;BMPR2
Accession
Species
 Human/Mouse
Biotinylated
 no
Amino Acid Range
 Ser27-Thr150
Molecular Weight
 The protein has a predicted MW of 39.84 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human/Mouse BMPR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human/Mouse BMPR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human/Mouse BMPR2 is greater than 95% as determined by SEC-HPLC. The purity of Human/Mouse BMPR2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...