Product Description |
Recombinant Human MRC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly31-Pro530. |
Product Background |
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. |
Product Category |
Recombinant Protein |
Target |
MRC2 |
Synonyms |
C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein (UPAR-associated protein; Urokinase receptor-associated protein) |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly31-Pro530 |
Molecular Weight |
The protein has a predicted MW of 57.64 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human MRC2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human MRC2 is greater than 95% as determined by SEC-HPLC. |
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