- Express System: HEK293
- Product Tag: C-His
- Purity: > 95% as determined by Bis-Tris PAGE
- Activity: Immobilized Human MSPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSPR Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.
- Amino Acid Range: Glu25-Leu571
Human MSPR/Ron-Protein (RON-HM101) Summary
Product Description |
Recombinant Human MSPR/Ron-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu25-Leu571. |
Product Background |
Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages. |
Human MSPR/Ron-Protein (RON-HM101) Specifications/Details
Protein |
MSPR/Ron |
Synonyms |
MSP receptor; CDw136; p185-Ron; CD136; MSP R; MSP receptor; MSPR; MST1R; PTK8; RON;p185Ron |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu25-Leu571 |
Molecular Weight |
The protein has a predicted MW of 59.71 kDa. Due to furin cleavage, the protein migrates to 70-80 kDa (full length) and 40-50 kDa (alpha chain) and 35-40 kDa (partial beta chain) based on Bis-Tris PAGE result. |
Activity |
Immobilized Human MSPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSPR Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: