Human MUC1 Isoform Y Protein (MUC-HM2Y1)
Catalog: MUC-HM2Y1
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| Product Description | Recombinant Human MUC1 Isoform Y Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gly158. |
Product Background |
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. |
Product Category |
Recombinant Protein |
Target |
MUC1 Isoform Y |
Gene/Protein ID |
P15941-7 |
Species |
Human |
Exact Sequence |
Ser24-Gly158 |
| Molecular Weight | The protein has a predicted MW of 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human MUC1 Isoform Y is greater than 95% as determined by SEC-HPLC. |
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Human MUC1 Isoform Y on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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