Human MUC1 Isoform Y Protein (MUC-HM2Y1)
Human MUC1 Isoform Y Protein (MUC-HM2Y1)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser24-Gly158
Catalog #MUC-HM2Y1
Regular price $412.50
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Product Description

Recombinant Human MUC1 Isoform Y Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gly158.

Product Background

MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.

Product Category

Recombinant Protein / Antibody discovery

Protein

MUC1 Isoform Y

Synonyms

MUC1/Y; MUC1; MUC-1; Mucin-1; Mucin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227;

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ser24-Gly158

Molecular Weight

The protein has a predicted MW of 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human MUC1 Isoform Y on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human MUC1 Isoform Y on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human MUC1 Isoform Y is greater than 95% as determined by SEC-HPLC. The purity of Human MUC1 Isoform Y is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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