Human Mucin-5AC Protein (MUC-HM2AC) Summary
Product Description |
Recombinant Human Mucin-5AC Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Gly4862-Pro5620. |
Product Background |
MUC5AC is a secreted gel-forming mucin expressed in normal mucus-producing cells of the stomach, the lung, and the uterine cervix as well as in cancer cells of the ovarian, the pancreas, and the gastrointestinal tract. In the colon, MUC5AC is expressed in scattered normal epithelial cells but can be abundant in colorectal cancers. |
Human Mucin-5AC Protein (MUC-HM2AC) Specifications/Details
Protein |
Mucin-5AC |
Synonyms |
MUC-5AC; MUC5AC; MUC5; Gastric Mucin; LeB; TBM |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly4862-Pro5620 |
Molecular Weight |
The protein has a predicted MW of 107.64 kDa. Due to glycosylation, the protein migrates to 200-250 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: