Human Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein (MUK-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu24-Thr495
Catalog #MUK-HM101
Regular price $379.50
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Human Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein (MUK-HM101) Summary

Product Description

Recombinant Human Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Thr495.

Product Background

MuSK (muscle-specific kinase) is a receptor tyrosine kinase that plays a central signaling role in the formation of neuromuscular junctions (NMJs). MuSK is activated in a complex spatio-temporal manner to cluster acetylcholine receptors on the postsynaptic (muscle) side of the synapse and to induce differentiation of the nerve terminal on the presynaptic side.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein (MUK-HM101) Specifications/Details

Protein
Musk (muscle, skeletal receptor tyrosine-protein kinase)
Synonyms
EC:2.7.10.1; MuSK; Muscle-specific kinase receptor
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu24-Thr495
Molecular Weight
The protein has a predicted MW of 53.46 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human Musk (muscle, skeletal receptor tyrosine-protein kinase) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Musk (muscle, skeletal receptor tyrosine-protein kinase) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Musk (muscle, skeletal receptor tyrosine-protein kinase) is greater than 95% as determined by SEC-HPLC. The purity of Human Musk (muscle, skeletal receptor tyrosine-protein kinase) is greater than 95% as determined by SEC-HPLC.
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