Human Nectin-1/PVRL1/CD111 Protein (NEC-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human Nectin-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human Nectin-1, hFc Tag with the EC50 of 19.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Exact Sequence: Gln31-Thr334

Catalog: NEC-HM201

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Product Description Recombinant Human Nectin-1/PVRL1/CD111 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Gln31-Thr334.

Product Background

Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such have been alternately named poliovirus receptor-related proteins.Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between Nectin-1 and Nectin-3 and between Nectin-1 and Nectin-4. Has some neurite outgrowth-promoting activity.

Product Category

Recombinant Protein

Target

Nectin-1/PVRL1/CD111

Gene/Protein ID

Q15223-1

Species

Human

Exact Sequence

Gln31-Thr334
Molecular Weight The protein has a predicted MW of 59.89 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Nectin-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human Nectin-1, hFc Tag with the EC50 of 19.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Nectin-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human Nectin-1, hFc Tag with the EC50 of 19.6ng/ml determined by ELISA (QC Test).
Immobilized Human Nectin-4, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Nectin-1, hFc Tag with the EC50 of 0.27ug/ml determined by ELISA.
The purity of Human Nectin-1 is greater than 95% as determined by SEC-HPLC.
Human Nectin-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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