Human Nectin-2/CD112 Protein (NEC-HM002)

  • Express System: HEK293
  • Product Tag: No Tag
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human Nectin-2, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human PVRIG, mFc Tag with the EC50 of 0.19ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln32-Leu360

Catalog: NEC-HM002

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Product Description Recombinant Human Nectin-2/CD112 Protein is expressed from HEK293 without tag.It contains Gln32-Leu360.

Product Background

Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.

Product Category

Recombinant Protein

Target

Nectin-2/CD112
Accession

Species

Human

Amino Acid Range

Gln32-Leu360
Molecular Weight The protein has a predicted MW of 35.54 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Nectin-2, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human PVRIG, mFc Tag with the EC50 of 0.19ug/ml determined by ELISA. See testing image for detail.

Product Tag

No Tag

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human Nectin-2, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human PVRIG, mFc Tag with the EC50 of 0.19ug/ml determined by ELISA.
The purity of Human Nectin-2 is greater than 95% as determined by SEC-HPLC.
Human Nectin-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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