Product Description |
Recombinant Human Netrin receptor DCC Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains His26-Asn1097. |
Product Background |
DCC (Deleted in Colorectal Cancer) is a single-pass transmembrane protein that belongs to the immunoglobulin superfamily. It was originally identified as a prognostic tumor marker and then subsequently found to be a receptor for netrin-1. DCC plays a key role in axon guidance and also in a number of other important cellular processes. |
Product Category |
Recombinant Protein |
Target |
Netrin receptor DCC |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
His26-Asn1097 |
Molecular Weight |
The protein has a predicted MW of 144.27 kDa. Due to glycosylation, the protein migrates to 140-160 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human Netrin receptor DCC on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Netrin receptor DCC is greater than 95% as determined by SEC-HPLC. |
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