Human NKG2C&CD94 Protein (NKC-HM696)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 1.65 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94)
Catalog #NKC-HM696
Regular price $315.00
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Product Description
Recombinant Human NKG2C&CD94 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94).
Product Background
NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
Product Category
Recombinant Protein
Target
NKG2C&CD94
Synonyms
NKG2C&CD94
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94)
Molecular Weight
The protein has a predicted MW of 15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 1.65 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
N-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human NKG2C&CD94, His Tag immobilized on CM5 Chip can bind Human HLA-E*01:03 Complex Tetramer, His Tag with an affinity constant of 1.65 uM as determined in SPR assay (Biacore T200).
Human NKG2C&CD94 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human NKG2C&CD94 is greater than 95% as determined by SEC-HPLC.

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