Human NKp46/NCR1/CD335 Protein (NKP-HM146)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human NKp46, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln22-Asn254

Catalog: NKP-HM146

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Product Description Recombinant Human NKp46/NCR1/CD335 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln22-Asn254.

Product Background

NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Product Category

Recombinant Protein

Target

NKp46/NCR1/CD335
Synonyms CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
Accession

Species

Human

Amino Acid Range

Gln22-Asn254
Molecular Weight The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human NKp46, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human NKp46, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA.
The purity of Human NKp46 is greater than 95% as determined by SEC-HPLC.
Human NKp46 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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