Human NKp46/NCR1/CD335 Protein (NKP-HM246)
Human NKp46/NCR1/CD335 Protein (NKP-HM246)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human NKp46, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 13.1ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln22-Asn255
Catalog #NKP-HM246
Regular price $315.00
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Product Description
Recombinant Human NKp46/NCR1/CD335 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Asn255.
Product Background
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
Product Category
Recombinant Protein
Target
NKp46/NCR1/CD335
Synonyms
CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gln22-Asn255
Molecular Weight
The protein has a predicted MW of 53.2 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human NKp46, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 13.1ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human NKp46, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 13.1ng/ml determined by ELISA.
Human NKp46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human NKp46 is greater than 95% as determined by SEC-HPLC.

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