Product Description |
Recombinant Human NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447. |
Product Background |
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
NOGOR |
Synonyms |
Nogo receptor; RTN4R; NOGOR; NgR1; Nogo-66 receptor; NGR |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Cys27-Ser447 |
Molecular Weight |
The protein has a predicted MW of 46.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human NOGOR, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human NOGOR, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA. |
|
|
Human NOGOR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human NOGOR is greater than 95% as determined by SEC-HPLC. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed
