Human NRAS-Protein (NRS-HE101)
Human NRAS-Protein (NRS-HE101)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Met1-Cys186
Catalog #NRS-HE101
Regular price $330.00
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Product Description

Recombinant Human NRAS-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Cys186.

Product Background

NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.

Product Category

Recombinant Protein / Antibody discovery

Protein

NRAS

Synonyms

GTPase NRas; N-Ras; HRAS1; ALPS4; CMNS;

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Met1-Cys186

Molecular Weight

The protein has a predicted MW of 22.29 kDa same as Bis-Tris PAGE result.

Product Tag

N-His

Expression System

E.coli

Purity

> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human NRAS on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human NRAS on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human NRAS-is greater than 90% as determined by SEC-HPLC. The purity of Human NRAS-is greater than 90% as determined by SEC-HPLC.

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