Name: Human NRG1 Beta 1 Protein (NRG-HM1B1)
Brand: KactusBio
SKU: NRG-HM1B1-100UG
Price: 239.8 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test).
Amino Acid Range: Ser177-Glu241
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Catalog #NRG-HM1B1

Size

100UG

500UG

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Human NRG1 Beta 1 Protein (NRG-HM1B1) Summary

Product Description	Recombinant Human NRG1 Beta 1 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Ser177-Glu241.
Product Background	Neuregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB), and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor, which increases the expression of the β2 subunit of the γ- aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human NRG1 Beta 1 Protein (NRG-HM1B1) Specifications/Details

Protein	NRG1 Beta 1
Synonyms	Pro-NRG1; NRG1; GGF; HGL; HRGA; NDF; SMDF; Beta1; Beta1A
Accession	Q02297-6
Species	Human
Biotinylated	no
Amino Acid Range	Ser177-Glu241
Molecular Weight	The protein has a predicted MW of 8.57 kDa. Due to glycosylation, the protein migrates to 10-13 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test).
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 50mM NaAc, 150mM NaCl (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test).
	Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her4, hFc Tag with the EC50 of 33.4ng/ml determined by ELISA.
	Human NRG1 Beta 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.