Human NRG1 Beta 1 Protein (NRG-HM1B1)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: >95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser177-Glu241
Catalog #NRG-HM1B1
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Product Description
 Recombinant Human NRG1 Beta 1 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Ser177-Glu241.
Product Background
 Neuregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB), and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor, which increases the expression of the β2 subunit of the γ- aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor.
Product Category
 Recombinant Protein
Target
 NRG1 Beta 1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ser177-Glu241
Molecular Weight
 The protein has a predicted MW of 8.57 kDa. Due to glycosylation, the protein migrates to 10-13 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 N-His
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in 50mM NaAc, 150mM NaCl (pH 5.0).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA (QC Test).
Immobilized Human NRG1 Beta 1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Her4, hFc Tag with the EC50 of 33.4ng/ml determined by ELISA.
Human NRG1 Beta 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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