Human OGN/Osteoglycin Protein (OGN-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Pro21-Phe298
Catalog #OGN-HM101
Regular price $346.50
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Product Description

Recombinant Human OGN/Osteoglycin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro21-Phe298.

Product Background

Osteoglycin (OGN, a.k.a. mimecan) belongs to cluster III of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM). In vertebrates OGN is a characteristic ECM protein of bone. The function of OGN has mainly been studied in mammals in which it regulates collagen fibrillogenesis, the efficiency of which is increased when it is processed by BMP-1/Tolloid-like metalloproteinases. OGN has a role in wound healing in the cornea, in atherosclerotic lesions and modulates myocardial integrity and remodelling. In addition, OGN enhances the neurite outgrowth promoted by insulin-like growth factor-2 and IGF binding protein-2.

Product Category

Recombinant Protein / Antibody discovery

Protein

OGN/Osteoglycin

Synonyms

Osteoglycin; OIF; OGN; SLRR3A

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Pro21-Phe298

Molecular Weight

The protein has a predicted MW of 32.83 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human OGN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human OGN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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