SDS-PAGE gel image showing protein ladder and a purified protein band indicating high expression and purity level.
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Pro21-Phe298
  • Other Available Proteins:
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Catalog #OGN-HM101
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Human OGN/Osteoglycin Protein (OGN-HM101) Summary

Product Description

 Recombinant Human OGN/Osteoglycin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro21-Phe298.

Product Background

 Osteoglycin (OGN, a.k.a. mimecan) belongs to cluster III of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM). In vertebrates OGN is a characteristic ECM protein of bone. The function of OGN has mainly been studied in mammals in which it regulates collagen fibrillogenesis, the efficiency of which is increased when it is processed by BMP-1/Tolloid-like metalloproteinases. OGN has a role in wound healing in the cornea, in atherosclerotic lesions and modulates myocardial integrity and remodelling. In addition, OGN enhances the neurite outgrowth promoted by insulin-like growth factor-2 and IGF binding protein-2.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human OGN/Osteoglycin Protein (OGN-HM101) Specifications/Details

Protein
 OGN/Osteoglycin
Synonyms
 Osteoglycin; OIF; OGN; SLRR3A
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Pro21-Phe298
Molecular Weight
 The protein has a predicted MW of 32.83 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human OGN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human OGN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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support@kactusbio.us

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