Human OSMR-GPL fusion Protein (OSG-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human OSMR-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Met1-Ala428(OSMR) & Leu21-Glu225(GPL)

Catalog: OSG-HM101

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Product Description Recombinant Human OSMR-GPL fusion Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ala428 (OSMR) and Leu21-Glu225 (GPL).

Product Background

OSMR involvement, together with Gp130-like receptor (GPL), also known as IL-31R, in the formation of a functional IL-31 receptor complex. OSMR-GPL fusion protein was designed to contain the domains of OSMR and GPL required for high affinity IL-31 binding.

Product Category

Recombinant Protein

Target

OSMR-GPL fusion

Gene/Protein ID

Q99650-1(OSMR)&Q8NI17-1(GPL)

Species

Human

Exact Sequence

Met1-Ala428(OSMR) & Leu21-Glu225(GPL)
Molecular Weight The protein has a predicted MW of 75.84 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human OSMR-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human OSMR-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.
Human OSMR-GPL fusion Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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