• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human OSMR beta-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.
  • Amino Acid Range: Met1-Ala428(OSMR beta) & Leu21-Glu225(GPL)
Catalog #OSG-HM101
Price
Regular price $41250
Regular price Sale price $41250
/
Size
Avantor VWR Fisher Scientific

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Human OSMR beta-GPL fusion Protein (OSG-HM101) Summary

Product Description

 Recombinant Human OSMR beta-GPL fusion Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ala428 (OSMR beta) and Leu21-Glu225 (GPL).

Product Background

 OSMR involvement, together with Gp130-like receptor (GPL), also known as IL-31R, in the formation of a functional IL-31 receptor complex. OSMR-GPL fusion protein was designed to contain the domains of OSMR and GPL required for high affinity IL-31 binding.

Human OSMR beta-GPL fusion Protein (OSG-HM101) Specifications/Details

Protein
 OSMR beta-GPL fusion
Synonyms
 OSMR-GPL
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Ala428(OSMR beta) & Leu21-Glu225(GPL)
Molecular Weight
 The protein has a predicted MW of 75.84 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human OSMR beta-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human OSMR beta-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. Immobilized Human OSMR beta-GPL fusion Protein, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.
Human OSMR beta-GPL fusion Protein on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human OSMR beta-GPL fusion Protein on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
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