Human OSMR Protein (OSM-HM10D)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Glu28-Val236

Catalog: OSM-HM10D

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Product Description Recombinant Human OSMR Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu28-Val236.

Product Background

OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.

Product Category

Recombinant Protein

Target

OSMR

Gene/Protein ID

Q99650-1

Species

Human

Exact Sequence

Glu28-Val236
Molecular Weight The protein has a predicted MW of 25.09 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA.
The purity of Human OSMR is greater than 95% as determined by SEC-HPLC.
Human OSMR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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