Human OSMR Protein (OSM-HM10D)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Glu28-Val236
Catalog #OSM-HM10D
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Product Description
 Recombinant Human OSMR Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu28-Val236.
Product Background
 OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category
 Recombinant Protein
Target
 OSMR
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Glu28-Val236
Molecular Weight
 The protein has a predicted MW of 25.09 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA.
Human OSMR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human OSMR is greater than 95% as determined by SEC-HPLC.

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