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Human PC2/Polycystin-2 Nanodisc (PC2-HM10N) Summary
Product Description |
Recombinant Human PC2/Polycystin-2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val968. |
Product Background |
Polycystin-2 (PC2) is a calcium channel that can be found in the endoplasmic reticulum, the plasmatic membrane, and the primary cilium. Functions include receptor-operated, nonselective cation channel activity in the plasma membrane, intracellular Ca2+ release channel activity in the endoplasmic reticulum (ER), and mechanosensitive channel activity in the primary cilium of renal epithelial cells. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Human PC2/Polycystin-2 Nanodisc (PC2-HM10N) Specifications/Details
Protein |
PC2/Polycystin-2 |
Synonyms |
Polycystin-2; Polycystin 2; PC2; Polycystwin; R48321; PKD2; TRPP2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val968 |
Molecular Weight |
The protein has a predicted MW of 111.6 kDa. |
Activity |
Immobilized Human PC2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PC2 Antibody, Rabbit Fc Tag with the EC50 of 28.2ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human PC2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PC2 Antibody, Rabbit Fc Tag with the EC50 of 28.2ng/ml determined by ELISA. |
Other Available Proteins:
Finding available proteins...
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