Target |
PCSK9 |
Synonyms |
PC9; PCSK9; FH3; HCHOLA3; LDLCQ1; NARC-1 |
Gene/Protein ID |
Q8NBP7-1 |
Species |
Human |
Exact Sequence |
Gln31-Gln692 |
Molecular Weight |
Due to autocatalytic cleavage, the protein release the pro-form (59 kDa) and mature form (14 kDa). Due to glycosylation, the protein migrates to 65-68 kDa (pro-form) and 15kDa (mature form) based on Tris-Bis PAGE result. |
Activity |
Immobilized Human PCSK9, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-PCSK9 antibody, hFc Tag with the EC50 of 0.16μg/ml determined by ELISA (QC Test). The affinity constant of 0.35 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per μg by the LAL method. |