Human PD-L1/B7-H1 Protein (PDL-HM610)

  • Express System: HEK293
  • Product Tag: C-Llama Fc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human PD-L1, LIama Fc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-1, mFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Phe19-Arg238

Catalog: PDL-HM610

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Product Description Recombinant Human PD-L1/B7-H1 Protein is expressed from HEK293 with Llama Fc tag at the C-terminus.It contains Phe19-Arg238.

Product Background

B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.

Product Category

Recombinant Protein

Target

PD-L1/B7-H1

Gene/Protein ID

Q9NZQ7-1

Species

Human

Exact Sequence

Phe19-Arg238
Molecular Weight The protein has a predicted MW of 52.50 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human PD-L1, LIama Fc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-1, mFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-Llama Fc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human PD-L1, LIama Fc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-1, mFc Tag with the EC50 of 0.17ug/ml determined by ELISA.
The purity of Human PD-L1 is greater than 95% as determined by SEC-HPLC.
Human PD-L1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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