Product Description |
Recombinant Human PGLYRP1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln22-Pro196. |
Product Background |
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. |
Product Category |
Recombinant Protein |
Target |
PGLYRP1 |
Synonyms |
PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln22-Pro196 |
Molecular Weight |
The protein has a predicted MW of 21.04 kDa. Due to glycosylation, the protein migrates to 27-37 kDa based on Bis-Tris PAGE result. |
Activity |
The affinity constant of 0.54 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human TREM1, His Tag immobilized on CM5 Chip can bind Human PGLYRP1, His Tag with an affinity constant of 0.54 uM as determined in SPR assay (Biacore T200). |
|
|
Human PGLYRP1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human PGLYRP1 is greater than 95% as determined by SEC-HPLC. |
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