Human PGLYRP1 Protein (PGL-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: The affinity constant of 0.54 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln22-Pro196
Catalog #PGL-HM101
Regular price $315.00
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Product Description

Recombinant Human PGLYRP1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln22-Pro196.

Product Background

Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.

Product Category

Recombinant Protein

Protein

PGLYRP1

Synonyms

PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln22-Pro196

Molecular Weight

The protein has a predicted MW of 21.04 kDa. Due to glycosylation, the protein migrates to 27-37 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.54 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TREM1, His Tag immobilized on CM5 Chip can bind Human PGLYRP1, His Tag with an affinity constant of 0.54 uM as determined in SPR assay (Biacore T200). Human TREM1, His Tag immobilized on CM5 Chip can bind Human PGLYRP1, His Tag with an affinity constant of 0.54 uM as determined in SPR assay (Biacore T200).
Human PGLYRP1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human PGLYRP1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human PGLYRP1 is greater than 95% as determined by SEC-HPLC. The purity of Human PGLYRP1 is greater than 95% as determined by SEC-HPLC.

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