Human PGLYRP1 Protein (PGL-HM201)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.
Exact Sequence: Gln22-Pro196

Catalog: PGL-HM201

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Product Description	Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.
Product Background	Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
Product Category	Recombinant Protein

Target	PGLYRP1
Synonyms	PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7
Gene/Protein ID	O75594
Species	Human
Exact Sequence	Gln22-Pro196
Molecular Weight	The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
	The purity of Human PGLYRP1 is greater than 95% as determined by SEC-HPLC.
	Human PGLYRP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.