Human PGLYRP1 Protein (PGL-HM201)
Catalog: PGL-HM201
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Product Description | Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196. |
Product Background |
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. |
Product Category |
Recombinant Protein |
Target |
PGLYRP1 |
Synonyms | PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7 |
Gene/Protein ID |
O75594 |
Species |
Human |
Exact Sequence |
Gln22-Pro196 |
Molecular Weight | The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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