Human PGLYRP1 Protein (PGL-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Gln22-Pro196

Catalog: PGL-HM201

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Product Description Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.

Product Background

Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.

Product Category

Recombinant Protein

Target

PGLYRP1
Synonyms PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7

Gene/Protein ID

O75594

Species

Human

Exact Sequence

Gln22-Pro196
Molecular Weight The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
The purity of Human PGLYRP1 is greater than 95% as determined by SEC-HPLC.
Human PGLYRP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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