Human PILRA Protein (PRA-HM101)
Human PILRA Protein (PRA-HM101)
Human PILRA Protein (PRA-HM101)
Human PILRA Protein (PRA-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 8.9ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln20-Ala197
Catalog #PRA-HM101
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Product Description
 Recombinant Human PILRA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln20-Ala197.
Product Background
 Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Product Category
 Recombinant Protein
Target
 PILRA
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gln20-Ala197
Molecular Weight
 The protein has a predicted MW of 21.32 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 8.9ng/ml determined by ELISA. See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 8.9ng/ml determined by ELISA.
Human PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human PILRA is greater than 95% as determined by SEC-HPLC.
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