Name: Human PILRA Protein (PRA-HM201)
Brand: KactusBio
SKU: PRA-HM201-100UG
Price: 270.0 USD
Availability: InStock

Catalog #PRA-HM201

Size

100UG

500UG

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Product Description	Recombinant Human PILRA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln20-Ala197.
Product Background	Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Product Category	Recombinant Protein / Antibody discovery

Protein	PILRA
Synonyms	PILRA; FDF03; PILRalpha; PILR-alpha
Accession	Q9UKJ1-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln20-Ala197
Molecular Weight	The protein has a predicted MW of 47 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human PILRA is greater than 95% as determined by SEC-HPLC.