Name: Human PLAU/uPA Protein (pro form) (PLA-HM102)
Brand: KactusBio
SKU: PLA-HM102-100UG
Price: 330.0 USD
Availability: InStock

Human PLAU/uPA Protein (pro form) (PLA-HM102)

Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.

Human PLAU (pro form) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human PLAU (pro form) is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.
Amino Acid Range: Ser21-Leu431

Catalog #PLA-HM102

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human PLAU/uPA Protein (pro form) (PLA-HM102) Summary

Product Description	Recombinant Human PLAU/uPA Protein (pro form) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Leu431.
Product Background	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human PLAU/uPA Protein (pro form) (PLA-HM102) Specifications/Details

Protein	PLAU/uPA
Synonyms	PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
Accession	P00749-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser21-Leu431
Molecular Weight	The protein has a predicted MW of 47.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.
	Human PLAU (pro form) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human PLAU (pro form) is greater than 95% as determined by SEC-HPLC.