Name: Human PLVAP Protein (PVP-HM101)
Brand: KactusBio
SKU: PVP-HM101-100UG
Price: 346.5 USD
Availability: InStock

Catalog #PVP-HM101

Size

100UG

500UG

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Product Description	Recombinant Human PLVAP Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr49-Gly442.
Product Background	Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier; however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases.
Product Category	Recombinant Protein / Antibody discovery

Protein	PLVAP
Synonyms	FELS; PV1
Accession	Q9BX97
Species	Human
Biotinylated	no
Amino Acid Range	Tyr49-Gly442
Molecular Weight	The protein has a predicted MW of 45.97 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.