Product Description |
Recombinant Human PRAK Protein is expressed from Baculovirus-Insect Cells with Strep-II tag at the C-terminus.It contains Met1-Gln471. |
Product Background |
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway. |
Product Category |
Recombinant Protein |
Target |
PRAK |
Synonyms |
MAPKAPK5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Gln471 |
Molecular Weight |
The protein has a predicted MW of 55.57 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-Strep-II |
Express System |
Baculovirus-Insect Cells |
Purity |
> 90% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 150mM NaCl, 2mM CaCl2 (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human PRAK on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
|
|
The purity of Human PRAK is greater than 95% as determined by SEC-HPLC. |
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