Name: Human PRLR Protein (PLR-HM201)
Brand: KactusBio
SKU: PLR-HM201-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human PRLR, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-PRLR Antibody, hFc Avi Tag with the EC50 of 7.9ng/ml determined by ELISA.
Amino Acid Range: Gln25-Asp234

Catalog #PLR-HM201

Size

100UG

500UG

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Human PRLR Protein (PLR-HM201) Summary

Product Description	Recombinant Human PRLR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Gln25-Asp234.
Product Background	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human PRLR Protein (PLR-HM201) Specifications/Details

Protein	PRLR
Synonyms	PRL-R; HPRL; MFAB; Prolactin R
Accession	P16471-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln25-Asp234
Molecular Weight	The protein has a predicted MW of 50.36 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human PRLR, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-PRLR Antibody, hFc Avi Tag with the EC50 of 7.9ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human PRLR, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-PRLR Antibody, hFc Avi Tag with the EC50 of 7.9ng/ml determined by ELISA.
	Human PRLR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human PRLR is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

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