Human PS20 Protein (PS2-HE120)
Catalog: PS2-HE120
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Product Description | Recombinant Human PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys32-Gln220. |
Product Background |
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection. |
Product Category |
Recombinant Protein |
Target |
PS20 |
Synonyms | Ps20; Wfdc1 |
Gene/Protein ID |
Q9HC57 |
Species |
Human |
Exact Sequence |
Lys32-Gln220 |
Molecular Weight | The protein has a predicted MW of 22 kDa. The protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
E.coli |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 200mM L-arginine (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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