Product Description |
Recombinant Human PSCA-Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Leu12-Ser86. |
Product Background |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. |
Product Category |
Recombinant Protein |
Target |
PSCA |
Synonyms |
PSCA; UNQ206; PRO232 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu12-Ser86 |
Molecular Weight |
The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. |
|
|
Human PSCA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human PSCA-is greater than 95% as determined by SEC-HPLC. |
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