Name: Human PSCA-Protein (PCA-HM201)
Brand: KactusBio
SKU: PCA-HM201-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: N-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 77.4ng/ml determined by ELISA.
Amino Acid Range: Leu12-Ser86

Catalog #PCA-HM201

Size

100UG

500UG

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Human PSCA-Protein (PCA-HM201) Summary

Product Description	Recombinant Human PSCA-Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Leu12-Ser86.
Product Background	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Human PSCA-Protein (PCA-HM201) Specifications/Details

Protein	PSCA
Synonyms	PSCA; UNQ206; PRO232
Accession	O43653
Species	Human
Biotinylated	no
Amino Acid Range	Leu12-Ser86
Molecular Weight	The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 77.4ng/ml determined by ELISA.
Product Tag	N-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 77.4ng/ml determined by ELISA.
	Human PSCA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human PSCA-is greater than 95% as determined by SEC-HPLC.