Human PSCA-Protein (PCA-HM201)
Human PSCA-Protein (PCA-HM201)
Human PSCA-Protein (PCA-HM201)
Human PSCA-Protein (PCA-HM201)
Human PSCA-Protein (PCA-HM201)
Human PSCA-Protein (PCA-HM201)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu12-Ser86
Catalog #PCA-HM201
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Product Description
 Recombinant Human PSCA-Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Leu12-Ser86.
Product Background
 Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer.
Product Category
 Recombinant Protein
Target
 PSCA
Synonyms
 PSCA; UNQ206; PRO232
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Leu12-Ser86
Molecular Weight
 The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.
Product Tag
 N-hFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human PSCA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Antibody, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA.
Human PSCA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human PSCA-is greater than 95% as determined by SEC-HPLC.
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