Product Description |
Recombinant Human PTP alpha/PTPRA Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Ala183-Lys802. |
Product Background |
The receptor protein-tyrosine phosphatase α (encoded by PTPRA), a 130-kDa transmembrane PTP, has shown to be a physiological regulator for PTK c-Src and the kinases involved in integrin signaling pathway including FAK and P130cas. The activation of PTPRA on Src Y530 dephosphorylation led to cellular transformation, which suggested that PTPRA might be an oncogenic gene. |
Product Category |
Recombinant Protein |
Target |
PTP alpha/PTPRA |
Synonyms |
R-PTP-alpha; PTPRA; PTPA; PTPRL2; PTP alpha; HEPTP; HLPR; HPTPA; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala183-Lys802 |
Molecular Weight |
The protein has a predicted MW of 73.00 kDa. The protein migrates to 68-75 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
Baculovirus-Insect Cells |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 20% glycerol, 3mM DTT (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human PTP alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
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