Human PTP alpha/PTPRA Protein (PTP-HB10A)
  • Express System: Baculovirus-Insect Cells
  • Product Tag: C-His
  • Purity: > 90% as determined by Bis-Tris PAGE
  • Amino Acid Range: Ala183-Lys802
Catalog #PTP-HB10A
Regular price $345.00
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Product Description
Recombinant Human PTP alpha/PTPRA Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Ala183-Lys802.
Product Background
The receptor protein-tyrosine phosphatase α (encoded by PTPRA), a 130-kDa transmembrane PTP, has shown to be a physiological regulator for PTK c-Src and the kinases involved in integrin signaling pathway including FAK and P130cas. The activation of PTPRA on Src Y530 dephosphorylation led to cellular transformation, which suggested that PTPRA might be an oncogenic gene.
Product Category
Recombinant Protein
Target
PTP alpha/PTPRA
Synonyms
R-PTP-alpha; PTPRA; PTPA; PTPRL2; PTP alpha; HEPTP; HLPR; HPTPA;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala183-Lys802
Molecular Weight
The protein has a predicted MW of 73.00 kDa. The protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
Baculovirus-Insect Cells
Purity
> 90% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 20% glycerol, 3mM DTT (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human PTP alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

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