Name: Human RGM-C Domain Protein (RGM-HM30D)
Brand: KactusBio
SKU: RGM-HM30D-100UG
Price: 379.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human RGM-C Domain, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln36-Pro145

Catalog #RGM-HM30D

Size

100UG

500UG

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Product Description	Recombinant Human RGM-C Domain Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Gln36-Pro145.
Product Background	RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	RGM-C
Synonyms	Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
Accession	Q6ZVN8-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln36-Pro145
Molecular Weight	The protein has a predicted MW of 37.43 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human RGM-C Domain, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-mFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human RGM-C Domain, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA (QC Test).
	Human RGM-C Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human RGM-C Domain is greater than 95% as determined by SEC-HPLC.