Human Semaphorin 4A/SEMA4A Ig-like Domain Protein (SEM-HM2D3) Summary
Product Description |
Recombinant Human Semaphorin 4A/SEMA4A Ig-like Domain Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Asn573-Phe631. |
Product Background |
Neuroimmune semaphorin 4A (Sema4A), a member of semaphorin family of transmembrane and secreted proteins, is an important regulator of neuronal and immune functions. In the nervous system, Sema4A primarily regulates the functional activity of neurons serving as an axon guidance molecule. In the immune system, Sema4A regulates immune cell activation and function, instructing a fine tuning of the immune response. |
Human Semaphorin 4A/SEMA4A Ig-like Domain Protein (SEM-HM2D3) Specifications/Details
Protein |
Semaphorin 4A/SEMA4A |
Synonyms |
Semaphorin-4A; Semaphorin-B; SEMA4A |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asn573-Phe631 |
Molecular Weight |
The protein has a predicted MW of 32.21 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 8% trehalose (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: