Product Description |
Recombinant Human Serpin F1/PEDF Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln20-Pro418. |
Product Background |
Pigment epithelium-derived factor (PEDF) is an important antiangiogenic and antitumorigenic factor in a variety of cancer forms, including pancreatic cancer. PEDF is mainly secreted as a soluble monomeric glycoprotein. In human pancreatic cancer PEDF levels are decreased, both in the tissue and serum. The decrease is associated with increased tumor angiogenesis, fibrosis, inflammation, autophagy, occurrence of liver metastasis and worse prognosis. |
Product Category |
Recombinant Protein |
Target |
Serpin F1/PEDF |
Synonyms |
PEDF; EPC-1; Serpin F1; SERPINF1; PIG35 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln20-Pro418 |
Molecular Weight |
The protein has a predicted MW of 45.5 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human Serpin F1/PEDF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Serpin F1/PEDF is greater than 95% as determined by SEC-HPLC. |
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