Name: Human SEZ6 Sushi4 Domain Protein (SEZ-HM20D)
Brand: KactusBio
SKU: SEZ-HM20D-100UG
Price: 380.0 USD
Availability: InStock

Human SEZ6 Sushi4 Domain Protein (SEZ-HM20D)

Human SEZ6 Sushi4 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human SEZ6 Sushi4 Domain is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gln769-Leu832

Catalog #SEZ-HM20D

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human SEZ6 Sushi4 Domain Protein (SEZ-HM20D) Summary

Product Description	Recombinant Human SEZ6 Sushi4 Domain Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Gln769-Leu832.
Product Background	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human SEZ6 Sushi4 Domain Protein (SEZ-HM20D) Specifications/Details

Protein	SEZ6
Synonyms	SEZ-6; SEZ6; BSRPC; BSRP-C
Accession	Q53EL9-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln769-Leu832
Molecular Weight	The protein has a predicted MW of 32.94 kDa. Due to glycosylation, the protein migrates to 40-48 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human SEZ6 Sushi4 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human SEZ6 Sushi4 Domain is greater than 95% as determined by SEC-HPLC.