Human SEZ6L Protein (SEZ-HM10L)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu29-Ala958
Catalog #SEZ-HM10L
Regular price $379.50
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Human SEZ6L Protein (SEZ-HM10L) Summary

Product Description

Recombinant Human SEZ6L Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu29-Ala958.

Product Background

SEZ6L, or seizure-related 6-like protein, is a neuronal protein implicated in various neurological conditions. It plays a role in motor coordination and anxiety-related behavior in mice, with SEZ6L-deficient mice displaying motor phenotypes and increased anxiety. Additionally, SEZ6L is involved in synaptic connectivity regulation and has been associated with bipolar disorder. It interacts with BACE1, the protease linked to Alzheimer's disease, suggesting its role in neurodegenerative processes.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human SEZ6L Protein (SEZ-HM10L) Specifications/Details

Protein
SEZ6L
Synonyms
Seizure 6-like protein; KIAA0927; UNQ2542/PRO6094;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu29-Ala958
Molecular Weight
The protein has a predicted MW of 103 kDa. Due to glycosylation, the protein migrates to 140-160 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human SEZ6L on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human SEZ6L on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human SEZ6L is greater than 95% as determined by SEC-HPLC. The purity of Human SEZ6L is greater than 95% as determined by SEC-HPLC.
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