Name: Human Siglec-15/CD33L3 Protein (SIG-HM215)
Brand: KactusBio
SKU: SIG-HM215-100UG
Price: 315.0 USD
Availability: InStock

Human Siglec-15/CD33L3 Protein (SIG-HM215)

Immobilized Human Siglec-15, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 22.4ng/ml determined by ELISA.

Human Siglec-15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Siglec-15, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 22.4ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Lys24-Gly260

Catalog #SIG-HM215

Size

100UG

500UG

Order now, ships by:

[{"id":42618394542302,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"SIG-HM215-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human Siglec-15\/CD33L3 Protein (SIG-HM215) - 100UG","public_title":"100UG","options":["100UG"],"price":31500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584265945310,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"SIG-HM215-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human Siglec-15\/CD33L3 Protein (SIG-HM215) - 500UG","public_title":"500UG","options":["500UG"],"price":105000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human Siglec-15/CD33L3 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys24-Gly260.
Product Background	Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
Product Category	Recombinant Protein / Antibody discovery

Protein	Siglec-15/CD33L3
Synonyms	CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15
Accession	Q6ZMC9-1
Species	Human
Biotinylated	no
Amino Acid Range	Lys24-Gly260
Molecular Weight	The protein has a predicted MW of 52.6 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Siglec-15, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 22.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM NaAC (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 20mM NaAC (pH 5.0).
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Siglec-15, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 22.4ng/ml determined by ELISA.
	Human Siglec-15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.